Due to large demand, registration for the symposium is now closed. To be put on a waiting list in the event another participant cancels, please e-mail RegenerativeMedicine@lmbps.com. 

Recent advances in diverse areas of biomedical science and breakthroughs in technology such as affordable whole genome sequencing and molecular profiling provide a unique opportunity to study the genetics and pathogenesis of a wide variety of human diseases with the eventual goal of using this information to inform clinical practice. Heterogeneity of patient populations and the absence of effective means to interpret patient genetic/omic information for clinical use are significant ostacles toward achieving this goal.

The purpose of the symposium is to provide opportunity for biologists and clinicians to exchange ideas, interact and enhance collaborations in advancing animal disease models to overcome some of the most difficult challenges in the post-genomic era, namely, to validate disease-associated genetic variations and biomarkers in humans, to reduce drug candidate attrition and develop new types of individualized therapies for both monogenic and complex human disorders.

Session Topics

1. The Use of Comparative and Functional Genomics to Build Animal Models of Human Diseases

2. Technological Advances and Available Resources for Building Predictive Animal Models

3. Using Personalized Animals for Drug Discovery and Biomarker Development

4. Which Human Disease Conditions Are the Best Candidates for Use of Personalized Animal Models?

5. How Personalized Animal Models Can Guide Clinical Trials

The symposium has several goals:

1. To discuss the status of human personalized genomics and the use of comparative functional genomics in other organisms to interpret patient information for clinical use.

2. To review the current status of the development and use of the personalized animal models based upon variety of animal species.

3. To evaluate the potential of the use of personalized animal models for translational medicine applications.

4. To develop the consensus and provide recommendations to the NIH regarding the potential strategic initiatives which would have a valuable contribution to the field.

Meeting Facility

The symposium will be held at the Natcher Conference Center (Building 45) on the NIH Bethesda campus, 9000 Rockville Pike, Bethesda, MD 20892. Allow extra time to get through the security checkpoint at the visitor’s entrance to campus. Since parking is limited, it’s recommended that visitors travel via Metrorail, which has a convenient stop (Medical Center) adjacent to the NIH Gateway Center. Gateway Center is located next door to the Natcher Conference Center.

·         For information on traveling to NIH, go to http://www.nih.gov/about/visitor/index.htm.

·         For a map of the NIH campus, go to http://www.ors.od.nih.gov/maps/Pages/NIH-Visitor-Map.aspx.

·         For a Metrorail map, go to http://www.wmata.com/rail/maps/print_map.cfm.

Meeting Days and Times

October 28, 2013: 8:30 a.m. – 5:55 p.m. Onsite check-in begins at 7:30 a.m.

October 29, 2013: 8:30 a.m. – 2:20 p.m.

Registration

To register, complete the registration form located on this site. On-line registration closes on September 25, 2013, so register early! After September 25, registration will continue by phone. Contact details coming soon.
 
For more information on meeting logistics and registration, contact:
RegenerativeMedicine@lmbps.com 
 
For questions about the symposium program, please contact: 
Oleg Mirochnitchenko,
PhD Health Scientist AdministratorDCM/ORIP/Division of Program Coordination, Planning, and Strategic Initiatives
Office of the Director, National Institutes of Health (NIH)
6701 Democracy Blvd, Suite 943
Bethesda, MD 20892
Tel:  301-435-0744
Fax: 301-480-3819