Mechanisms of Lung Injury and Immunomodulator Interventions in Influenza
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 Mechanisms of Lung Injury and
Immunomodulator Interventions in Influenza Workshop

The clinical course of influenza and the extent of lung injury are determined by the balance between viral replication and the host immune response.  Lung injury in severe influenza infections is frequently due to an over exuberant host inflammatory response.  This workshop aims to review the current understanding of lung injury in acute influenza and to describe cellular and molecular mechanisms of lung injury that are common to influenza and other pathogens.  In addition, therapeutic agents that target host response proteins and pathways will be identified and investigational agents in development will be reviewed.  A better understanding of common cell signaling pathways associated with acute lung injury caused by influenza and other agents is necessary in order to understand host immunopathologic causes of lung injury, to determine which immunomodulatory interventions might be useful and to predict subsequent consequences of their use.

 

Objectives of meeting:

·         To describe the current understanding of mechanisms of lung injury in acute influenza

·         To identify mechanisms of lung injury that are common to influenza and other pathogens

·         To identify potential therapeutic targets and review investigational agents in development

 

This workshop will take place on March 21, 2010 in Ventura, CA and will be held in conjunction with the Gordon Research Conference (GRC) on the “Biology of Acute Respiratory Infections” to be held at the same location on March 21-26, 2010 in Ventura, CA.  The Mechanisms of Lung Injury and Immunomodulator Interventions in Influenza Workshop will be held on the first day, March 21, and registration for the GRC will begin that same evening.  Combining these two events will provide attendees with the opportunity to attend the annual GRC and network with colleagues.  Please visit the GRC tab, on this registration website, for more information.
 
This workshop is dedicated to the memory of Dr. Jerry Donlon.
 
 
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